1H-Pyrrole-3-carboxylic acid, 4-methyl-, ethyl ester

1H-Pyrrole-3-carboxylic acid, 4-methyl-, ethyl ester - Names and Identifiers

Name	Ethyl 4-methylpyrrole-3-carboxylate
Synonyms	3-CARBETHOXY-4-METHYLPYRROLE 1,4-Benzenediamine,2,8-dibromo- Ethyl 4-methylpyrrole-3-carboxylate ETHYL 4-METHYLPYRROLE-3-CARBOXYLATE ethyl 4-methyl-1H-pyrrole-3-carboxylate Ethanone,1-(2-pyridinyl)-2-(9-quinolinyl)- 4-Methyl-3-pyrrolecarboxylic acid ethyl ester 4-methyl-1H-pyrrole-3-carboxylic acid ethyl ester 1H-Pyrrole-3-carboxylic acid, 4-methyl-, ethyl ester
CAS	2199-49-7
InChI	InChI=1/C8H11NO2/c1-3-11-8(10)7-5-9-4-6(7)2/h4-5,9H,3H2,1-2H3

1H-Pyrrole-3-carboxylic acid, 4-methyl-, ethyl ester - Physico-chemical Properties

Molecular Formula	C8H11NO2
Molar Mass	153.18
Density	1.106±0.06 g/cm3 (20 ºC 760 Torr)
Melting Point	72-75°C
Boling Point	289.7±20.0℃ (760 Torr)
Flash Point	129.0±21.8℃
Solubility	Slightly Soluble (2.3 g/L) at 25°C
Vapor Presure	0.00216mmHg at 25°C
pKa	15.72±0.50(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.517
MDL	MFCD00030417

1H-Pyrrole-3-carboxylic acid, 4-methyl-, ethyl ester - Risk and Safety

Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.

1H-Pyrrole-3-carboxylic acid, 4-methyl-, ethyl ester - Introduction

Ethyl is an organic compound with the chemical formula C9H11NO2. It is a colorless liquid with a special smell. Here are some of its properties:

Nature:
1. Density: about 1.07 g/cm
2. Melting Point: About -30 ℃
3. Boiling point: About 220 ℃
4. Refractive index: about 1.513
5. Solubility: Soluble in some organic solvents, such as ether and chloroform

Use:
Ethyl L has certain applications in organic synthesis, mainly for the synthesis of other compounds. It can also be used as a pharmaceutical intermediate for the synthesis of some drugs.

Method: The synthesis of
Ethyl L usually uses a four-member reaction, which reacts an appropriate amount of Ethyl acetate and pyrrole with methanol under the action of a strong acid catalyst (such as sulfuric acid) to obtain the target product. The synthesis process needs to pay attention to safety and avoid touching strong acids and harmful substances.

Safety Information:
1. Ethyl L is an organic compound and should be stored in a dry, well-ventilated place, away from fire and oxidizing agents.
2. During the operation should wear appropriate protective gloves, protective glasses and protective clothing. Avoid contact with skin and inhalation of gases or vapours.
3. If the compound is inhaled or ingested, seek medical advice immediately and bring the container or label for the compound.
4. This compound may be toxic to aquatic organisms, should avoid pollution to the environment. Observe local regulations when discarding.

Last Update：2024-04-09 19:05:47